TABLE 4.
PI-G8 myoblasts are completely cured of persistent infection by anti-CVB1 treatment
| Horse serum | Serum added | CPE/viral RNA detected at passagea:
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | ||
| Preimmune | p30-p35 | +/+ | +/+ | +/+ | +/+ | +/+ | +/+ | +/+ | +/+ |
| Anti-CVB1 | p30-p35 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
| Preimmune | p30-p31 | +/+ | +/+ | +/+ | +/+ | +/+ | NAb | NA | NA |
| Anti-CVB1 | p30-p31 | −/− | −/− | −/− | −/− | −/− | NA | NA | NA |
a
Results indicate that cultures were consistently positive (+) or negative (−) for virus-induced CPE or viral RNA (detected by RT-PCR) at a given passage. Uninfected G8 cells were uniformly negative when run as a negative control for detection of CPE and viral RNA.
b
NA, not assayed for CPE or viral RNA at these passages.