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. 2024 Jul 26;48(4):546–708. doi: 10.4093/dmj.2024.0249
1. All people with diabetes should be screened for diabetic peripheral neuropathy (DPN) and autonomic neuropathy, starting at 5 years after diagnosis of T1DM and at the time of diagnosis of T2DM, and annually thereafter. [Expert opinion, general recommendation]
2. Screening for DPN should include the Michigan Neuropathy Screening Instrument Questionnaire (MNSIQ) and neurological examination (tests for vibration perception, ankle reflex, 10-g monofilament, pin-prick sensation, and temperature sensation). [Expert opinion, general recommendation]
3. In the presence of symptoms of diabetic autonomic neuropathy (such as resting tachycardia, orthostatic hypotension, gastroparesis, constipation, diarrhea, fecal incontinence, erectile dysfunction, voiding dysfunction, urinary incontinence, sweating of the body trunk and face, or anhidrosis of the lower extremities), tests for cardiovascular autonomic neuropathy (CAN), GI autonomic nervous function, urodynamics, and sweating are required. [Expert opinion, limited recommendation]
4. Strict glycemic management is necessary, as adequate glycemic control prevents or delays the development and progression of DPN and CAN in both T1DM and T2DM. [Randomized controlled trial, general recommendation]
5. For individuals with painful diabetic neuropathy, assess the pain and initiate medical treatment to control pain and improve quality of life. [Randomized controlled trial, general recommendation]
6. For all individuals with diabetes, it is recommended to conduct an annual comprehensive assessment for risk factors of ulcers and amputation, and provide education on foot care. [Expert opinion, general recommendation]
7. Perform peripheral angiography in people with severe claudication, weak dorsal artery pulse, or an ankle-brachial index of ≤0.9. [Randomized controlled trial, limited recommendation]
8. A multidisciplinary approach is required for diabetic foot ulcers (DFUs). [Expert opinion, general recommendation]