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. Author manuscript; available in PMC: 2024 Aug 8.
Published in final edited form as: Ann Intern Med. 2023 Mar 21;176(4):489–495. doi: 10.7326/M22-3469

Table.

Percentage Resistance of Candida auris Isolates Tested by the Antimicrobial Resistance Laboratory Network, 2018 to 2020*

Year or Region Azoles Amphotericin B Echinocandins§

Year
 2018 (n = 463) 372 (80.3) 151 (32.6) 2 (0.4)
 2019 (n = 1006) 787 (78.2) 242 (24.1) 14 (1.4)
 2020 (n = 1294) 1109 (85.7) 331 (25.6) 15 (1.2)
Region
 Mid-Atlantic (n = 135) 133 (98.5) 115 (85.2) 4 (3.0)
 Midwest (n = 156) 17 (10.9) 2 (1.4) 0 (0.0)
 Mountain (n = 25) 24 (96.0) 1 (4.0) 0 (0.0)
 Northeast (n = 1051) 1046 (99.5) 468 (44.5) 22 (2.1)
 Southeast (n = 172) 170 (99.4) 9 (5.2) 0 (0.0)
 West (n = 556) 553 (99.5) 17 (3.1) 1 (0.2)
*

Data are numbers (percentages). Numbers are based on records with any minimum inhibitory concentrations (MICs). About 1% of all records for all times were missing MICs for 1 or 2 drug classes.

The tentative MIC breakpoint for fluconazole was ≥32 mcg/mL.

The tentative MIC breakpoint for amphotericin B was ≥2 mcg/mL.

§

The tentative MIC breakpoint for echinocandins was ≥4 mcg/mL (anidulafungin or micafungin).

The Central region is excluded because of the small number of isolates.