Figure 4.

Experimental design. Single-pulse TMS was applied to map motor threshold on day 1. Rats underwent sessions of high-frequency pulse trains on days 2-4, one type of pulse train (TS100, TS166, or TS250) on a given day, randomized across animals. There were 7 power levels at each frequency; ten pulse trains were administered at each power level, and each pulse train consisted of ten pulses. The order of the 7 power levels was randomized as well. There were 5 min intervals between these power levels to minimize potential aftereffects from prior pulse trains. Abbreviations: TS100, TS166, and TS250 denote pulse train at 100, 166, and 250 Hz, respectively. Abbreviations: IPI, inter-pulse interval. ITI, inter-train interval.