Table 2.
Clinical and Vestibular Comparison Between Patients With and Without Oscillopsia (Group 1/Group 2) at 3 Postoperative Months.
| Variable | Group 1 (n = 9) | Group 2 (n = 6) | P value |
|---|---|---|---|
| Sex (male/female) | 4/5 (44.4%/55.6%) | 3/3 (50%/50%) | .05 |
| Mean age (y) | 56.11 ± 10.97 | 62.50 ± 10.37 | .34 |
| Dominant hand (R/L) | 9/0 (100%/0%) | 4/2 (66.7%/33.3%) | .06 |
| HAD anxiety scale | 8.22 ± 4.02 | 8.0 ± 2.94 | >.99 |
| HAD depression scale | 4.00 ± 3.74 | 3.25 ± 3.95 | .90 |
| Optical correction | 7 (77.8%) | 1 (16.7%) | / |
| Progressive glasses | 7/7 (100%) | 1 (16.7%) | / |
| Port all day | 7/7 (100%) | 1 (16.7%) | / |
| Initial etiology | |||
| Meniere’s disease | 7 (77.8%) | 5 (83.3%) | .79 |
| Multiples crisis | 2/7 (28.6%) | 2/5 (40%) | .68 |
| Tumarkin syndrome | 5/7 (71.4%) | 3/5 (60%) | .68 |
| Others (schwannoma) | 2 (22.2%) | 1 (16.7%) | / |
| Age of the disease (vestibular) | 3.19 ± 2.04 | 7.14 ± 9.09 | .54 |
| Neurectomy side (R/L) | 4/5 (44.4%/55.6%) | 3/3 (50%/50%) | .83 |
| Vertigo attack | 0 (0%) | 0 (0%) | / |
| Instability | 7 (77.8%) | 5 (83.3%) | .79 |
| Disabling nature of instability | |||
| Little or not disabling | 4 (44.4%) | 4 (66.7%) | .4 |
| Quite disabling | 5 (55.6%) | 1 (16.7%) | / |
| Disabling | 0 (0%) | 0 (0%) | / |
| Very disabling | 0 (0%) | 1 (16.7%) | / |
| OSQ (mean) | 2.10 ± 0.63 | 1.24 ± 0.28 | .01* |
| Disabling nature of oscillopsia | |||
| Little or not disabling | 5 (55.6%) | 6 (100%) | .06 |
| Quite disabling | 3 (33.3%) | 0 (0%) | / |
| Disabling | 1 (11.1%) | 0 (0%) | / |
| Very disabling | 0 (0%) | 0 (0%) | / |
| Resumption of driving | 8 (100%) (n = 8) | 3 (50%) | .1 |
| Resumption of activities/walking >1 h/d | 8 (88.9%) | 5 (83.3%) | .76 |
| Spontaneous nystagmus (°/s) (preoperative) | 0.8 ± 2.06 | 1.35 ± 2.03 | .71 |
| Spontaneous nystagmus (°/s) (postoperative) | 1.52 ± 1.45 | 1.85 ± 1.12 | .31 |
| Kinetic tests (sinusoïde 0.1 Hz) (preoperative) | |||
| Gain | 0.78 ± 0.3 | 0.59 ± 0.31 | .22 |
| Preponderance (AV) | 4.2 ± 3.52 | 4.81 ± 3.5 | .8 |
| Kinetic tests (sinusoïde 0.1 Hz) (postoperative) | |||
| Gain | 0.53 ± 0.17 | 0.54 ± 0.23 | .67 |
| Preponderance (AV) | 2.98 ± 1.65 | 2.75 ± 2.11 | .19 |
| Caloric tests (preoperative) | |||
| Ipsilateral reflexivity | 15.84 | 9.04 | .28 |
| contralateral reflexivity | 26.37 | 26.16 | .98 |
| Deficit (%) ipsilateral | 36 | 46.5 | .14 |
| Caloric tests (postoperative) | 8 (100%) (n = 8) | 6 (100%) | NC |
| Preoperative vHIT | |||
| Preoperative VOR gain of ipsilateral SCC | |||
| Anterior (A) | 0.95 ± 0.10 | 0.82 ± 0.11 | .06 |
| Lateral (L) | 0.87 ± 0.11 | 0.81 ± 0.21 | .93 |
| Posterior (P) | 0.85 ± 0.16 | 0.80 ± 0.20 | .40 |
| Preoperative VOR gain of contralateral SCC | |||
| Anterior (A) | 1.04 ± 0.09 | 0.94 ± 0.13 | .18 |
| Lateral (L) | 0.98 ± 0.04 | 0.87 ± 0.09 | .007* |
| Posterior (P) | 0.92 ± 0.10 | 0.79 ± 0.22 | .14 |
| Postoperative vHIT | |||
| Postoperative VOR gain of ipsilateral SCC (M3) | |||
| Anterior (A) | 0.44 ± 0.16 | 0.25 ± 0.22 | .07 |
| Lateral (L) | 0.06 ± 0.13 | 0.08 ± 0.17 | .97 |
| Posterior (P) | 0.38 ± 0.18 | 0.24 ± 0.13 | .26 |
| Postoperative VOR gain of contralateral SCC (M3) | |||
| Anterior (A) | 0.89 ± 0.11 | 0.79 ± 0.07 | .0496* |
| Lateral (L) | 0.91 ± 0.09 | 0.75 ± 0.15 | .03 |
| Posterior (P) | 0.7 ± 0.2 | 0.47 ± 0.21 | .0496* |
| First saccade latency | 136.9 ± 19.51 | 158.8 ± 25.25 (n = 5) | .14 |
| Preoperative DVA | |||
| Preoperative DVA loss | |||
| Static flash | 0.15 ± 0.12 | 0.13 ± 0.14 | .75 |
| Ipsilateral | 0.10 ± 0.13 | 0.17 ± 0.06 | .15 |
| Contralateral | 0.07 ± 0.11 | 0.11 ± 0.13 | .76 |
| Up | 0.10 ± 0.11 | 0.16 ± 0.08 | .28 |
| Down | 0.18 ± 0.14 | 0.24 ± 0.25 | .71 |
| Postoperative DVA | |||
| Postoperative DVA loss (M3) | |||
| Static flash | 0.10 ± 0.12 | 0.13 ± 0.17 | .77 |
| Ipsilateral | 0.32 ± 0.14 | 0.38 ± 0.15 | .46 |
| Contralateral | 0.25 ± 0.10 | 0.35 ± 0.26 | .77 |
| Up | 0.24 ± 0.09 | 0.29 ± 0.22 | .11 |
| Down | 0.25 ± 0.12 | 0.38 ± 0.23 | .46 |
| Postoperative delta DVA loss (M3) | |||
| Ipsilateral | −0.22 ± 0.13 | −0.21 ± 0.12 | .98 |
| Contralateral | −0.18 ± 0.10 | −0.24 ± 0.21 | .84 |
| Up | −0.14 ± 0.12 | −0.24 ± 0.20 | .44 |
| Down | −0.07 ± 0.16 | −0.14 ± 0.19 | .44 |
DVA losses are expressed in logMAR. Delta DVA loss is (preoperative DVA loss—postoperative DVA loss). Data are expressed as n (%) and mean standard deviation unless otherwise indicated.
Abbreviations: °/s, velocity in °/second; AV, absolute value; DVA, dynamic visual acuity; HAD, hospital anxiety and depression scale; L, left; M3, 3 months; OSQ, Oscillopsia Severity Questionnaire; R, right; SCC, semicircular canal; VOR, vestibuloocular reflex; *, statistically significant P value.