Table 1.
Demographic and Clinical Characteristics of Patients With Microscopic Colitis at Loyola University Medical Center, 2008–2018
| Variable | N | Summary statistic |
|---|---|---|
| Sex, n (%) | 269 | |
| Female | 214 (79.55) | |
| Male | 55 (20.45) | |
| Age (y), n (%) | 269 | |
| 65a | 159 (59.11) | |
| 49–64 | 80 (29.74) | |
| 34–48 | 20 (7.43) | |
| 19–33 | 10 (3.72) | |
| Age (y), n (%) | 269 | |
| > 50 | 235 (87.36) | |
| < 50 | 34 (12.64) | |
| Race, n (%) | 268 | |
| Asian | 4 (1.49) | |
| Black | 10 (3.73) | |
| Latino | 14 (5.22) | |
| Native American | 2 (0.75) | |
| White | 238 (88.81) | |
| Hormonal therapy, n (%) | 269 | |
| Multiple | 1 (0.37) | |
| Oral contraceptives | 20 (7.43) | |
| Hormone replacement therapy | 16 (5.95) | |
| IUD/Hormone secreting/Other | 5 (1.86) | |
| No hormonal therapy | 227 (84.39) | |
| Hormonal therapy, n (%) | 269 | |
| Yes | 42 (15.61) | |
| No | 227 (84.39) | |
| Smoking, n (%) | 269 | |
| Yes | 140 (52.04) | |
| No | 129 (47.96) | |
| History of diarrhea, n (%) | 269 | |
| Yes | 241 (89.59) | |
| No | 28 (10.41) | |
| Positive stool for pathogens, n (%) | 269 | |
| Yes | 18 (6.69) | |
| No | 251 (93.31) | |
| Alcohol use, n (%) | 269 | |
| Yes | 148 (55.02) | |
| No | 121 (44.98) | |
| Diabetes, n (%) | 269 | |
| Yes | 53 (19.70) | |
| No | 216 (80.30) | |
| HLD, n (%) | 269 | |
| Yes | 160 (59.48) | |
| No | 109 (40.52) | |
| CAD, n (%) | 269 | |
| Yes | 68 (25.28) | |
| No | 201 (74.72) | |
| HTN, n (%) | 269 | |
| Yes | 155 (57.62) | |
| No | 114 (42.38) | |
| IBS, n (%) | 269 | |
| Yes | 28 (10.41) | |
| No | 241 (89.59) | |
| Thyroid disease, n (%) | 269 | |
| Yes | 66 (24.54) | |
| No | 203 (75.46) | |
| Celiac disease, n (%) | 269 | |
| Yes | 12 (4.46) | |
| No | 257 (95.54) | |
| Autoimmune disease, n (%)a | 269 | |
| Yes1 | 31 (11.52) | |
| No | 238 (88.48) | |
| Probiotics, n (%) | 269 | |
| Yes | 76 (28.25) | |
| No | 193 (71.75) | |
| NSAIDs, n (%) | 269 | |
| Yes | 125 (46.47) | |
| No | 144 (53.53) | |
| Anticonvulsants, n (%) | 269 | |
| Yes | 17 (6.32) | |
| No | 252 (93.68) | |
| Statins, n (%) | 269 | |
| Yes | 143 (53.16) | |
| No | 126 (46.84) | |
| PPI, n (%) | 269 | |
| Yes | 111 (41.26) | |
| No | 158 (58.74) | |
| SSRIs, n (%) | 269 | |
| Yes | 96 (35.69) | |
| No | 173 (64.31) | |
| Tricyclic antidepressants, n (%) | 269 | |
| Yes | 26 (9.67) | |
| No | 243 (90.33) | |
| Aspirin, n (%) | 269 | |
| Yes | 130 (48.33) | |
| No | 139 (51.67) | |
| Beta-blocker, n (%) | 269 | |
| Yes | 99 (36.80) | |
| No | 170 (63.20) | |
| Plavix, n (%) | 269 | |
| Yes | 33 (12.27) | |
| No | 236 (87.73) | |
| H2 blocker, n (%) | 269 | |
| Yes | 62 (23.05) | |
| No | 207 (76.95) | |
| Antidiabetic, n (%) | 269 | |
| Yes | 52 (19.33) | |
| No | 217 (80.67) | |
| Microscopic colitis, n (%) | 265 | |
| Incomplete colitis (LCi/CCi) | 29 (10.94) | |
| Lymphocytic colitis (LC) | 100 (37.74) | |
| Collagenous colitis (CC) | 136 (51.32) | |
| Coronary artery disease, n (%) | 268 | |
| Yes | 45 (16.79) | |
| No | 223 (83.21) | |
| PAD, n (%) | 268 | |
| Yes | 23 (8.58) | |
| No | 245 (91.42) | |
| Thromboembolic disease, n (%) | 266 | |
| Yes | 6 (2.26) | |
| No | 260 (97.74) | |
| CVD, n (%) | 267 | |
| Yes | 20 (7.49) | |
| No | 247 (92.51) | |
| Hypertension, n (%) | 268 | |
| Yes | 156 (58.21) | |
| No | 112 (41.79) | |
| BMI, mean (SD) | 266 | 27.69 (6.46) |
| Systolic blood pressure (mmHg), mean (SD) | 267 | 129.29 (17.79) |
BMI, body mass index; IUD, intrauterine device; HLD, hyperlipidemia; HTN, hypertension; NSAIDs, non steroidal anti-inflammatory drugs; PPI, proton pump inhibitor; SD, standard deviation; SSRI, selective serotonin reuptake inhibitor.
a
Autoimmune disease other than celiac and thyroid disease.