Table 1.
Baseline Characteristics of the Study Patients (n = 1,389)
| Demographics | |
| Age (y) | 57 (45–65) |
| Sex (male/female) | 594 (42.8)/795 (57.2) |
| Body mass index (kg/m2) | 27.4 (24.8–30.6) |
| Diabetes mellitus (no/yes) | 887 (63.9)/502 (36.1) |
| Hypertension (no/yes) | 807 (58.1)/581 (41.9) |
| Dyslipidemia (no/yes) | 589 (42.4)/800 (57.6) |
| Laboratory values | |
| Platelet count (103/μL) | 215 (175–263) |
| Alanine aminotransferase (IU/L) | 73 (47–110) |
| Aspartate aminotransferase (IU/L) | 51 (35–74) |
| Gamma-gultamyl transpeptidase (IU/L) | 60 (40–99) |
| Albumin (g/dL) | 4.4 (4.1–4.6) |
| Total bilirubin (mg/dL) | 0.8 (0.6–1.0) |
| aMAP score | 51.3 (44.2–56.9) |
| aMAP score (0–50/50–60/60–100) | 620 (45.3)/545 (39.8)/203 (14.8) |
| FIB-4 index | 1.55 (0.90–2.62) |
| FIB-4 index (<1.30/1.30–2.67/>2.67) | 589 (42.4)/469 (33.8)/330 (23.8) |
| ALBI score | −2.96 (−3.18 to −2.70) |
| ALBI grade (≤ −2.60 / > −2.60 and ≤ −1.39 / > −1.39) | 1126 (83.2)/226 (16.7)/2 (0.1) |
| Histology | |
| Steatosis (0/1/2/3) | 8 (0.6)/974 (70.1)/271 (19.5)/136 (9.8) |
| Inflammation (0/1/2/3) | 67 (4.8)/879 (63.3)/364 (26.2)/79 (5.7) |
| Ballooning (0/1/2) | 452 (32.5)/611 (44.0)/326 (23.5) |
| NAS score | 4 (3–5) |
| NAS score (1–2/3–4/5–8) | 280 (20.2)/747 (53.8)/362 (26.1) |
| Fibrosis stage (0/1/2/3/4) | 240 (17.3)/536 (38.6)/394 (28.4)/195 (14.0)/24 (1.7) |
| NASH (no/yes) | 459 (33.0)/930 (67.0) |
Data are expressed as medians (interquartile range) or n (%).