Table 4.
Univariate and Multivariate Associations Between Patient Characteristics and Odds of Metachronous Advanced Colorectal Neoplasia
| Characteristic | Univariate OR (95% CI) | Multivariate aORa (95% CI) | P value |
|---|---|---|---|
| Race | |||
| Black vs White | 0.92 (0.69–1.24) | 0.96 (0.70–1.30) | .781 |
| Sex | |||
| Female vs male | 1.03 (0.77–1.39) | 1.10 (0.81–1.48) | .547 |
| Age | |||
| 10-y increase | 1.28 (1.04–1.57) | 1.24 (0.98–1.57) | .068 |
| Education | |||
| Less than high school | 1.03 (0.71–1.48) | 1.03 (0.71–1.49) | .891 |
| High-school graduate | Reference | Reference | – |
| Some college/college graduate | 1.21 (0.84–1.72) | 1.25 (0.87–1.79) | .237 |
| Insurance | |||
| Commercial | Reference | Reference | – |
| Free care | 0.70 (0.25–1.96) | 0.84 (0.29–2.37) | .737 |
| Medicaid | 1.08 (0.73–1.61) | 1.17 (0.77–1.77) | .464 |
| Medicare | 1.31 (0.94–1.82) | 1.18 (0.83–1.68) | .366 |
| Time since baseline examination | |||
| ≤3 y | 1.37 (0.97–1.95) | 1.10 (0.75–1.61) | .620 |
| 4–5 y | 1.12 (0.79–1.59) | 0.96 (0.67–1.39) | .842 |
| 5+ y | Reference | Reference | – |
| Indication for baseline examination | |||
| Surveillance vs screening | 1.27 (0.94–1.73) | 1.24 (0.90–1.72) | .190 |
| Findings from baseline examination | |||
| Normal/nonneoplastic polyps/other | Reference | Reference | – |
| Nonadvanced polyps | 0.89 (0.62–1.28) | 0.98 (0.67–1.44) | .935 |
| Multiplicity (3+ nonadvanced adenomas) | 1.30 (0.75–2.25) | 1.36 (0.76–2.41) | .298 |
| Hyperplastic polyps ≥10 mm | 1.12 (0.14–8.76) | 1.18 (0.15–9.26) | .874 |
| ACN (advanced/malignant polyps) | 1.89 (1.28–2.80) | 2.04 (1.34–3.09) | .001 |
a
Adjusted odds ratio controlling for race, sex, age, education, insurance, time since baseline examination (surveillance interval), indication for baseline examination, and findings at baseline examination.