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. Author manuscript; available in PMC: 2024 Aug 8.
Published in final edited form as: Clin Infect Dis. 2021 Nov 2;73(9):1617–1624. doi: 10.1093/cid/ciab449

Table 3.

Estimated Average Annual Incidence of Invasive H. influenzae Disease among Children Aged <5 years, by Serotype and Race — United States, 2008–2017

White Black Asian/PI AI/AN Total

Incidencea IRR Incidencea IRR
(95% CI)
Incidencea IRR
(95% CI)
Incidencea IRR
(95% CI)
Incidencea
NTHi 1.6 Ref 2.4 1.5
(1.2–1.9)
1.4 0.9
(0.6–1.4)
2.0 1.2
(0.7–2.3)
1.7
Hia 0.5 Ref 0.6 1.3
(0.9–1.9)
0.1 0.1
(0.0–0.8)
8.4 16.7
(11.7–24.0)
0.7
Hib 0.1 Ref 0.1 0.4
(0.1–1.3)
0.0 N/A 2.9 22.4
(11.9–42.1)
0.2
Hie 0.1 Ref 0.1 2.8
(1.0–7.1)
0.1 1.2
(0.1–8.9)
0.0 N/A 0.1
Hif 0.3 Ref 0.9 2.8
(1.9–4.2)
0.5 1.7
(0.9–3.5)
0.6 1.9
(0.6–5.7)
0.4
Total 2.6 Ref 4.1 1.6
(1.4–1.9)
2.0 0.8
(0.6–1.1)
13.8 5.3
(4.2–6.8)
3.0

Note: No cases of invasive disease due to H. influenzae serotypes c or d were reported among children aged <5 years.

a

Cases per 100,000 persons per year

Abbreviations: PI, Pacific Islander; AI/AN, American Indian and Alaska Native; IRR, Incidence Rate Ratio; CI, confidence interval; Ref, Reference category for IRR calculation; NTHi, nontypeable H. influenzae; Hia, H. influenzae serotype a; Hib, H. influenzae serotype b; Hie, H. influenzae serotype e; Hif, H. influenzae serotype f