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. 2022 Feb 3;1(1):93–105. doi: 10.1016/j.gastha.2021.10.008

Figure 4.

Figure 4

Role of the circadian clock in the pathogenesis and progression of NAFLD and NASH. Normal levels of circadian clock gene products inhibit the onset of NAFLD, whereas dysregulation in transcription products of circadian cycles is implicated in progression to NASH as well as progression to HCC. Library of Science & Medical Illustrations were utilized in part to create this figure. https://creativecommons.org/licenses/by-nc-sa/4.0/.