Central Illustration.

Summary of patient enrollment, follow-up metrics, and 6-month clinical and functional outcomes for the fully enrolled US cohort of the FLASH registry in pulmonary embolism.

The FLASH registry enrolled 800 patients with acute pulmonary embolism across 50 US sites who were undergoing treatment with mechanical thrombectomy using the FlowTriever System and followed them through 6 months postthrombectomy. Follow-up completion and mean duration of follow-up are reported, along with 6-month all-cause mortality. Clinical and functional outcomes assessed from baseline through 6 months include echocardiographic measurements of RV size and function, dyspnea using the modified Medical Research Council score, exercise capacity using the 6-minute walk test, quality of life using the PEmb-QoL score, and prevalence of chronic disease outcomes including CTEPH or CTED. CTED, chronic thromboembolic disease; CTEPH, chronic thromboembolic pulmonary hypertension; FLASH, FlowTriever All-comer Registry for Patient Safety and Hemodynamics; PEmb-QoL, Pulmonary Embolism Quality of Life; RV, right ventricular.