Meta-analyses comparing OCT-guided versus angiography-guided PCI. Risk reduction (95% CI) for the meta-analyses that reported on the comparison of OCT- versus angiography-guided PCI for (A) all-cause mortality, (B) cardiovascular mortality, (C) MACE, (D) myocardial infarction, (E) stent thrombosis, and (F) TLR. Point estimates in green indicate meta-analyses with randomized controlled trials only. Point estimates in blue represent meta-analyses of randomized controlled trials and observational studies. MACE, major adverse cardiac event; OCT, optical coherence tomography; PCI, percutaneous coronary intervention; TLR, target lesion revascularization.