Table 1.
Baseline clinical and angiographic characteristics.
| Characteristic | Women, n = 144 | Men, n = 484 | P value |
|---|---|---|---|
| Age, y | 74.2 ± 9.0 | 71.1 ± 8.8 | <.001 |
| Diabetes mellitus | 59 (41.0) | 182 (37.6) | .47 |
| Hypertension | 124 (86.1) | 415 (85.7) | .91 |
| Hyperlipidemia | 130 (90.3) | 401 (83.0) | .03 |
| Prior myocardial infarction | 23 (16.0) | 114 (23.6) | .053 |
| Prior coronary artery bypass grafting | 9 (6.3) | 51 (10.5) | .12 |
| Prior stroke or transient ischemic attack | 13 (9.0) | 41 (8.5) | .83 |
| Current or former smoker | 62/143 (43.4) | 295/480 (61.5) | <.001 |
| Renal insufficiencya | 45/143 (31.5) | 112/482 (23.2) | .046 |
| Pacemaker or ICD/CRT-D | 7 (4.9) | 32/483 (6.6) | .44 |
| Canadian Cardiovascular Society angina classification | .03 | ||
| Class 0 | 17/139 (12.2) | 72/476 (15.1) | |
| Class I | 21/139 (15.1) | 121/476 (25.4) | |
| Class II | 57/139 (41.0) | 171/476 (35.9) | |
| Class III | 42/139 (30.2) | 101/476 (21.2) | |
| Class IV | 2/139 (1.4) | 11/476 (2.3) | |
| Angiographic characteristic (core laboratory) | |||
| Target vessel | .43 | ||
| Protected left main | 0 (0.0) | 9 (1.9) | |
| Left anterior descending | 87 (60.4) | 281 (58.1) | |
| Left circumflex | 17 (11.8) | 58 (12.0) | |
| Right | 40 (27.8) | 136 (28.1) | |
| Reference vessel diameter, mm | 2.74 ± 0.43 | 3.02 ± 0.51 (481) | <.001 |
| Minimum lumen diameter, mm | 1.00 ± 0.43 | 1.08 ± 0.38 (481) | .04 |
| Diameter stenosis, % | 63.2 ± 12.2 | 63.9 ± 11.7 (481) | .52 |
| Lesion length, mm | 22.4 ± 10.3 | 25.0 ± 11.7 (480) | .01 |
| Calcium length, mm | 38.7 ± 18.1 | 42.4 ± 20.4 (479) | .052 |
| Severe calcificationb | 138 (95.8) | 471 (97.3) | .08 |
| Bifurcation lesion with side branch involvement | 33 (22.9) | 157 (32.4) | .03 |
Values are n (%), n/N (%), mean ± standard deviation, or mean ± standard deviation (n).
ICD/CRT-D, implantable cardiac defibrillator with or without bi-ventricular pacing capability
a
Estimated glomerular filtration rate (using the Modification of Diet in Renal Disease [MDRD] formula) < 60 mL/min/1.73 m2.
b
Defined as radiopaque densities noted without cardiac motion generally involving both sides of the arterial wall.