TABLE 3.

Logistic regression analysis of the combined WITS and ARIEL cohorts

Variablea	Parameter estimate	SE	Pr > chi squareb	Odds ratio
African-American ethnic group	−0.46	0.25	0.06	0.63
Mother received AZT	−0.49	0.33	0.13	0.61
Infant received AZT	0.82	0.47	0.08	2.28
Log of infant’s CD4 count	−0.51	0.24	0.04	0.60
Premature birth	0.37	0.28	0.18	1.45
Birth after February 1994	−1.25	0.46	0.01	0.29
Homozygous CCR5-59356T	1.35	0.59	0.02	3.84
Log of mother’s CD4 count	−0.55	0.14	0.00	0.57

^aLogistic regression analysis of the combined WITS and ARIEL cohorts (total of 656; 94 HIV-1 infected) based 1 df for each variable. Variables that were thought to influence transmission were included. The African-American ethnic group was included as a variable because the allele frequency for CCR5-59356T is far greater in that group. 

^bProbability that under the null hypothesis of no correlation with transmission, the observed data are attributable to chance alone.