Table. 3.
League Table Showing Comparisons Among Each Fibrosis Score in all Cases (N＝1059)
| Fibrosis score | Cutoff value (sensitivity/specificity [%]) | AUROC | 95% CI | AP20 | APP | APRI | FIB-4 index | FIB-3 index |
|---|---|---|---|---|---|---|---|---|
| AP20 (AST-3PLT+20) | 2.2 (71.5/66.6) | 0.745 | 0.713–0.777 | |||||
| APP (albumin platelet product) | 8.732 (68.1/67.3) | 0.730 | 0.696–0.764 | P = .352 | ||||
| APRI (AST platelet ratio index) | 2.184 (70.1/69.0) | 0.749 | 0.718–0.781 | P = .238 | P = .254 | |||
| FIB-4 index | 1.630 (70.1/71.5) | 0.773 | 0.742–0.804 | P = .024 | P = .0018 | P = .082 | ||
| FIB-3 index | 1.892 (73.5/69.0) | 0.774 | 0.744-0.805 | P <.0001 | P = .0022 | P = .0008 | P = .883 |
The FIB-3 index showed the best AUROC (0.774) among all indices for predicting F3 fibrosis or higher. The FIB-3 index showed significantly better AUROC than AP20 (p < 0.0001), APP (p = 0.0022), and APRI (p = 0.0008); however, no significant difference was observed between the FIB-3 and FIB-4 indices (p = 0.883).
CI, confidential interval.