Figure.

Abdominal ultrasonography revealed coarse and heterogeneous relatively hyperechoic hepatic parenchyma and an irregular isoechoic region (A). Contrast-enhanced CT revealed enhancement in the liver except for the region corresponding to the isoechoic region in the arterial phase (B). Gadolinium-ethoxybenzyl diethylenetriamine–enhanced magnetic resonance imaging revealed the region corresponding to the relatively hyperechoic hepatic parenchyma was clearly hypointense (C). Representative images of PAX8 immunohistochemical staining (D) and hematoxylin-eosin staining (E) in the coarse and heterogeneous relatively hyperechoic hepatic parenchyma. Arrows indicate PAX-8 positive cells. Arrowheads indicate the interlobular bile ducts destroyed by infiltration of inflammatory cells. Representative images of PAX8 immunohistochemical staining in the isoechoic region (F).