FIG. 2.

Patient TAN. (A) HTLV-1 viral DNA copy numbers from all available time points and their relationship to the onset of HAM/TSP (arrow) and therapy first with zidovudine (ZDV) and then with lamivudine (LMV) are shown for patient TAN. (B) Comparison of changes in the amount of HTLV-1 viral DNA (dashed line with squares) and HTLV-1 Tax-specific CTL effector frequency (solid line with diamonds) during therapy. (C) Comparison of the amount of HTLV-1 viral DNA (open squares) with changes in the percentage of lymphocytes expressing CD25 (solid diamonds) before, during, and after therapy with lamivudine. ZDV, zidovudine; LMV, lamivudine.