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. 1999 Dec;73(12):10310–10319. doi: 10.1128/jvi.73.12.10310-10319.1999

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Copyright © 1999, American Society for Microbiology

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FIG. 4 — Sequence analysis for IIIBx env clones 8x and S10 in comparison to HXBc2. Shaded regions indicate mutations that are also found in other clones from HIV-1/IIIB. Predicted N-linked glycosylation sites are indicated (), as are the positions of variable loops, the gp120/gp41 cleavage site, and the TM membrane-spanning domain (msd). 8x contains a frameshift mutation at position 706 resulting in a prematurely truncated TM cytoplasmic tail. S10 contains a deletion of 50 nt, which also leads to frameshift and a prematurely truncated TM cytoplasmic tail.

Inline graphic — Sequence analysis for IIIBx env clones 8x and S10 in comparison to HXBc2. Shaded regions indicate mutations that are also found in other clones from HIV-1/IIIB. Predicted N-linked glycosylation sites are indicated (), as are the positions of variable loops, the gp120/gp41 cleavage site, and the TM membrane-spanning domain (msd). 8x contains a frameshift mutation at position 706 resulting in a prematurely truncated TM cytoplasmic tail. S10 contains a deletion of 50 nt, which also leads to frameshift and a prematurely truncated TM cytoplasmic tail.