Table 4.
IL10 − 1082 A/G (rs1800896) among ALL patients and control group
IL10 − 1082 A/G (rs1800896) | Control n = 100 | ALL n = 100 | p - value | OR (95% CI) | |||
---|---|---|---|---|---|---|---|
N. | % | N. | % | ||||
Genotypes | AA | 50 | 50.0 | 13 | 13.0 | - | Reference |
AG | 46 | 46.0 | 40 | 40.0 | 0.001 | 2.078 (1.339–3.225) | |
GG | 4 | 4.0 | 47 | 47.0 | < 0.001 | 9.345 (5.059–17.262) | |
Dominant model | AA | 50 | 50.0 | 13 | 13.0 | - | Reference |
AG + GG | 50 | 50.0 | 87 | 87.0 | < 0.001 | 3.204 (2.125–4.831) | |
Recessive model | AA + AG | 96 | 96.0 | 53 | 53.0 | - | Reference |
GG | 4 | 4.0 | 47 | 47.0 | < 0.001 | 5.964 (3.460–10.279) | |
Alleles | A | 146 | 73.0 | 66 | 33.0 | - | Reference |
G | 54 | 27.0 | 134 | 67.0 | < 0.001 | 2.868 (2.213–3.716) |
N Number, OR Odds ratio, CI Confidence interval, Reference, according to NCBI database; A Adenine, G Guanine, P < 0.05 is considered significant; OR < 1 is considered protective; OR > 1 is considered risky