Table 1.

DISCOVER INOCA registry inclusion criteria.

Potential subjects must meet all of the following criteria to be eligible for inclusion in the study:

General inclusion criteria: •The patient is a male or nonpregnant female ≥18 y of age •The patient has suspected ischemic heart disease and is referred to undergo clinically indicated invasive coronary angiography •The patient has no obstructive coronary artery disease (CAD) as defined by (1) angiographically normal coronary arteries OR (2) nonobstructive CAD with angiographic stenosis <50%, or ≥50 but <70% with FFR ≥0.81 or RFR ≥0.90 •The patient is willing to comply with specified follow-up evaluations. The patient or legally authorized representative has been informed of the nature of the study, agrees to its provisions, and has been provided written informed consent approved by the appropriate institutional review board or ethics committee

CAD, coronary artery disease; FFR, fractional flow reserve; RFR, resting full cycle ratio.