Table 7.

Multivariate logistic regression analysis of risk factors for ECMO death.

Variable	Adjusted odds ratio (95% CI)	P value
On home oxygen prior to admit	10.47 (0.8768-125.0555)	.063
Initial serum lactate (mmol/L)	1.13 (1.0416-1.2287)	.003a
Initial platelet count (1000)	1.00 (0.99-1.00)	.067
Cardiac arrest	1.56 (0.13-19.20)	.728
Arrest site	1.04 (0.47-2.32)	.920
Arrest rhythm	0.84 (0.51-1.38)	.488
Total CPR time (min)	1.02 (0.99-1.05)	.181
Intubated prior to VA ECMO	2.18 (0.57-8.31)	.252
Initial SBP prior to VA ECMO	1.00 (0.99-1.02)	.629
Required vasopressors prior to VA ECMO	1.12 (0.38-3.32)	.843
Required inotropes prior to VA ECMO	0.94 (0.45-1.96)	.871
SAVE score prior to VA ECMO (unit)	0.92 (0.86-0.99)	.031a
SOFA score prior to VA ECMO (unit)	1.27 (1.15-1.40)	<.001a
LAVA ECMO	0.43 (0.16-1.20)	.109
Required blood transfusion post VA ECMO	0.39 (0.15-1.03)	.057
8-h serum lactate clearance (%)	0.99 (0.98-0.99)	.001a
AKI post VA ECMO	1.16 (0.57-2.37)	.689

Model inclusive of risk factors associated with ECMO death with a P value of <.05 on univariate analysis (Table 1, Table 2, Table 3, Table 4, Table 5, Table 6). Dependent variable = ECMO death defined as inpatient mortality while on ECMO circuit, or within 24 h of decannulation.

AKI, acute kidney injury; CPR, cardiopulmonary resuscitation; LAVA, left-atrial venoarterial; SAVE, survival after VA ECMO; SOFA, sequential organ failure assessment; VA ECMO, venoarterial extracorporeal membrane oxygenation.

^aSignificant P values.