Table 3.

Type 2 Diabetes and Risk of Early-onset Colorectal Cancer as Per Anatomical Site

Anatomical site	Participants with type 2 diabetes, no. (%)		Multivariable adjusted OR (95% CI)a	Multivariable adjusted OR (95% CI)b
	Cases	Controls
Colon cancerc	204 (5.3)	1946 (3.7)	1.43 (1.23–1.66)	1.32 (1.13–1.54)
Proximal colon	60 (5.2)	1946 (3.7)	1.48 (1.14–1.93)	1.35 (1.03–1.77)
Distal colon	72 (6.5)	1946 (3.7)	1.72 (1.35–2.19)	1.67 (1.30–2.15)
Unspecified colon	72 (4.6)	1946 (3.7)	1.19 (0.94–1.52)	1.06 (0.83–1.36)
Rectal cancerc	94 (4.6)	1946 (3.7)	1.22 (0.99–1.50)	1.13 (0.92–1.40)

^aAdjusted for the same set of covariates as model^a in Table 2.

^bAdjusted for the same set of covariates as model^b in Table 2.

^cA total of 41 cases with more than one anatomical site were excluded.