Weighted averages, 95% CIs, and forest plot for major bleeding (irrespective of BARC) in patients with high-risk pulmonary embolism. Additional information is presented in Supplemental Table S1. AC Grp., anticoagulation group; AC & ECMO, anticoagulation and extracorporeal membrane oxygenation group; BARC, Bleeding Academic Research Consortium; Surg. Embol. Grp., surgical embolization group.