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. 2024 Jul 20;18(1):wrae132. doi: 10.1093/ismejo/wrae132

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© The Author(s) 2024. Published by Oxford University Press on behalf of the International Society for Microbial Ecology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Bacteria–phage–gene network. (A) GCVDB viruses were connected to bacterial hosts (isolate and bMAG) according to the host prediction described in the methods and to metabolic and symbiosis genes according to their functional annotations. The ellipse indicates the position of viruses identified as keystones in the network analyses. (B) Alluvial plot displays abundant bacterial classes (left) linked to viral families (center) found to interact with them though CRISPR spacer and provirus linkages identified in this study. On the right, viral families are linked to metabolic genes encoded in their genomes.