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. Author manuscript; available in PMC: 2024 Aug 8.
Published in final edited form as: Clin Infect Dis. 2021 Aug 16;73(4):e938–e946. doi: 10.1093/cid/ciab053

Table 3:

Attributable body weight difference from birth to 5 years of age in children unexposed to intrapartum antibiotics (None), children exposed to intrapartum antibiotic prophylaxis as recommended for the prevention of perinatal group B streptococcal disease (GBS) and any other type or duration of intrapartum antibiotic administration (Other) stratified by delivery mode.

Vaginal delivery Cesarean delivery

None (weight gain, kg) GBS (Δ weight gain, kg) Other (Δ weight gain, kg) Other (weight gain, kg) GBS (Δ weight gain, kg)

Total cohort, N 113693 31263 11425 58684 8366
Reference Reference
Crude model 16.08 0.30 (0.29, 0.30) 0.12 (0.10, 0.13) 16.47 0.38 (0.36, 0.39)
Full Model 16.00 0.32 (0.31, 0.33) 0.16 (0.15, 0.18) 16.21 0.43 (0.41, 0.45)

Using the Full Model (Covariates through childhood) adjustment for demographics, maternal and birth-related factors included infant sex, gestational age at birth, birth weight, infant’s race/ethnicity (White, Black, Hispanic, Asian or Pacific Islander, other or unknown), year of birth, medical center of birth, maternal education, parity, maternal diabetes, maternal pre-pregnancy BMI, maternal gestational weight gain, maternal smoking during pregnancy, antepartum antibiotic exposure, neonatal antibiotic exposure, breastfeeding, indirect antibiotic exposure during breastfeeding, and childhood antibiotic exposure.