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. 2024 Feb 23;103(8):e37015. doi: 10.1097/MD.0000000000037015

Table 3.

Mitochondrial depolarization (JC-1) levels in flow cytometry of IC50 concentrations of Cl-amidine and carmustine in U-87 MG cells (control: 0.1% DMSO, n = 3, mean ± standard deviation).

Groups Viable cells % (upper quadrant) JC-1-positive cells % (lower quadrant)
Control 87.7 ± 2.0 12.3 ± 2.0
Cl-amidine 45.3 ± 11.51 54.7 ± 11.60
Carmustine 41.4 ± 3.80 58.6 ± 3.80

Cl-amidine = chlorine-amidine, DMSO = dimethyl sulfoxide, IC50 = half maximal inhibitory concentration, JC-1 = 5,5', 6,6'-tetrachloro-1,1', 3,3' tetraethyl benzimidazolyl carbocyanine iodide, U-87 MG = human glioblastoma cells.