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VSV infection leads to polykaryon formation in HEC cell lines. Cells were infected at an MOI of 2. At 24 hpi, the monolayers were fixed in methanol and stained with Giemsa stain. (a) Mock-infected HEC-1A cells; (b) HEC-1A cells infected with VSVIND; (c and d) mock- and VSVIND-infected HECA2 cells, respectively; (e) HECA2 cells infected with a recombinant vaccinia virus vector encoding the full-length G protein of VSVIND; (f) HECA2 cells infected with VSVNJ/CA.
