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. 2024 Jul 26;15:1388753. doi: 10.3389/fphar.2024.1388753

TABLE 2.

Comparison of the clinical features and serological parameters of the both trails at baseline.

Characteristics WWXDD Colchicine Difference
Baseline P
Age: mean (SD) 49.85 (15.85) 51.8 (19.6) 0.561
Male, n (%) 39 (95.12%) 34 (91.89%) 0.628
BMI: mean (SD) 25.21 (2.44) 26.99 (3.85) 0.051
First instance of gout, n (%) 7 (17.07%) 6 (16.22%) 0.92
Tophus, n (%) 12 (29.27%) 13 (35.14%) 0.579
Number of body parts affected, n (%) 1 20 (48.78%) 22 (59.56%) 0.779
2 13 (31.71%) 5 (13.51%)
3 5 (12.20%) 5 (13.51%)
4 2 (4.88%) 1 (2.70%)
≧5 1 (2.44%) 4 (10.81%)
Body part affected, n (%) metatarsophalangeal joint (MTPJ) 12 (29.27%) 14 (37.84%) 0.423
foot joints 28 (68.29%) 19 (51.35%) 0.127
Other lower limb 13 (31.71%) 12 (32.43%) 0.945
upper limb 14 (34.15%) 12 (32.43%) 0.873
Joint symptoms score, Q2 (Q1-Q3) 2 (2–4) 2 (2–4.5) 0.266
CRP mg/L, mean (SD) 37.11 (32.20) 27.33 (38.57) 0.133
Uric Acid (μmol/L), mean (SD) 494.63 (151.67) 490.54 (134.19) 0.90
ALT (U/L), mean (SD) 31.05 (20.11) 38.29 (40.87) 0.34
AST (U/L), mean (SD) 30.84 (33.29) 28.37 (27.46) 0.73
Cr (μmol/L), mean (SD) 88.10 (19.12) 81.41 (22.96) 0.28

MTPJ: metatarsophalangeal joint; CRP: C-reactive protein; ALT: alanine transaminase; AST: aspartate aminotransferase; Cr: Creatinine; SD: standard deviation.