TABLE 3.
Comparison of outcome measures at day 7 in both groups.
| Outcome measures | WWXDD | Colchicine | P | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | Day 7 | Mean difference (95%CI) | P intra | Baseline | Day 7 | Mean difference (95%CI) | P intra | Mean difference (95%CI) | P day 7 | |
| Joint symptoms score, Q2 (Q1-Q3) | 2 (2–4) | 0 (0–1) | <0.001 | 2 (2–4.5) | 0 (0–1) | <0.001 | 0.539 | |||
| CRP mg/L, mean (SD) | 37.11 (32.20) | 7.96 (13.97) | 28.66 (14.00–43.32) | 0.004 | 27.33 (38.57) | 6.65 (7.81) | 29.32 (7.93–50.71) | 0.008 | −0.9 (-21.90–6.47) | 0.71 |
| Uric Acid (μmol/L), mean (SD) | 494.63 (151.67) | 437.89 (139.61) | 56.74 (-15.16–128.64) | 0.120 | 490.54 (134.19) | 452.30 (116.42) | 38.24 (-29.66–106.13) | 0.26 | 14.41 (-58.95–87.77) | 0.70 |
| ALT (U/L), mean (SD) | 31.05 (20.11) | 29.63 (13.31) | 1.42 (-7.29–10.14) | 0.745 | 38.29 (40.87) | 42.25 (39.7) | −4.0 (-26.71–18.78) | 0.73 | 12.62 (-3.69–28.93) | 0.126 |
| AST (U/L), mean (SD) | 30.84 (33.29) | 26.33 (18.86) | 4.51 (-9.74–18.75) | 0.530 | 28.37 (27.46) | 26.20 (19.60) | 2.17 (-11.84–16.19) | 0.76 | −0.13 (-11.53–11.26) | 0.98 |
| Cr (μmol/L), mean (SD) | 88.10 (19.12) | 91.36 (22.69) | −3.27 (-14.83–128.64) | 0.745 | 81.41 (22.96) | 83.65 (22.74) | −2.24 (-15.18–10.70) | 0.73 | −7.7 (-21.90–6.47) | 0.29 |
CRP: C-reactive protein; ALT: alanine transaminase; AST: aspartate aminotransferase; Cr: Creatinine; SD: standard deviation.