Extended Data Fig. 1. SATURN integrates muscle cell types across three mammalian species.

UMAP visualization of SATURN’s embeddings obtained by integrating muscle tissues from human, mouse and lemur. Cells are colored based on broad-level cell types (left) and based on the species they come from (right). Epithelial and mesothelial cells types, which were only found within human, form a unique cluster (circled). To create each dataset, the larger Tabula datasets were subsetted. The human subset included cells labeled as muscle and vasculature. For mouse, limb muscle was chosen. For lemur, limb muscle and diaphragm were chosen. Human mesothelial cells belong to the tissue labeled muscle, and epithelial cells belong to the tissue labeled vasculature.