Extended Data Fig. 2. Reannotation of cells labeled as mouse macrophage in mouse muscle.
UMAP visualization of macrophage and granulocyte cell types obtained by integrating cells from human, mouse and lemur. (a) A small group of mouse macrophages cluster with granulocyte cell types from human (mast cells) and lemur (basophil) (circled), while other mouse macrophages cluster with human and lemur macrophages. These mouse cells (b) express Cd55, which has been shown to be preferentially expressed in granulocytes19,20, and (c) do not express Cd74, which has been shown to be preferentially expressed in macrophages and not expressed in granulocytes19,20. (b), (c) are colored by log-normalized expression.