Table 1.
Patient characteristics by practice research engagement
| Characteristics | All patients diagnosed with cancer | Community practices with high research engagement | Community practices with low research engagement | P |
|---|---|---|---|---|
| (n = 568 540) | (n = 328 694) | (n = 239 846) | ||
| Time from diagnosis to first clinical study drug use or November 1, 2017, 2017, mo | <.001 | |||
| Median (IQR) | 26.7 (12.4-44.0) | 26.6 (12.2-43.6) | 27.0 (12.7-44.3) | |
| No. of cancer treatment trial participants during study period, No. (%) | 11 315 (1.99) | 10 672 (3.25) | 643 (0.27) | <.001 |
| Age at November 1, 2017, y | <.001 | |||
| Median (IQR) | 66.0 (57.0-74.0) | 65.0 (56.0-73.0) | 66.0 (57.0-74.0) | |
| Age category, y, No. (%) | <.001 | |||
| 49 and younger | 75 972 (13.4) | 46 060 (14.0) | 29 912 (12.5) | |
| 50-64 | 187 932 (33.1) | 110 845 (33.7) | 77 087 (32.1) | |
| 65-74 | 174 954 (30.8) | 100 085 (30.4) | 74 869 (31.2) | |
| 75 and older | 129 682 (22.8) | 71 704 (21.8) | 57 978 (24.2) | |
| Sex, No. (%) | .526 | |||
| Male | 248 518 (43.7) | 143 795 (43.7) | 104 723 (43.7) | |
| Female | 320 022 (56.3) | 184 899 (56.3) | 135 123 (56.3) | |
| Race and ethnicity, No. (%) | <.001 | |||
| Asian | 12 677 (2.6) | 9014 (3.0) | 3663 (1.9) | |
| Black | 55 506 (11.2) | 30 532 (10.3) | 24 974 (12.6) | |
| Latinx | 41 217 (8.3) | 18 255 (6.1) | 22 962 (11.6) | |
| Not documented | 73 190 | 30 984 | 42 206 | |
| Othera | 42 046 (8.5) | 30 023 (10.1) | 12 023 (6.1) | |
| White | 343 904 (69.4) | 209 886 (70.5) | 134 018 (67.8) | |
| Eastern Cooperative Oncology Group performance status at index, No. (%) | <.001 | |||
| 0 | 267 255 (53.3) | 147 867 (50.2) | 119 388 (57.7) | |
| 1 | 174 241 (34.7) | 109 096 (37.0) | 65 145 (31.5) | |
| ≥2 | 60 185 (12.0) | 37 709 (12.8) | 22 476 (10.9) | |
| Unknown or missing | 66 859 | 34 022 | 32 837 | |
| Insurance type, No. (%) | <.001 | |||
| Commercial | 173 151 (30.5) | 104 830 (31.9) | 68 321 (28.5) | |
| Medicaid | 60 900 (10.7) | 35 745 (10.9) | 25 155 (10.5) | |
| Medicare | 191 065 (33.6) | 115 061 (35.0) | 76 004 (31.7) | |
| Other | 45 341 (8.0) | 28 337 (8.6) | 17 004 (7.1) | |
| Uninsured or unknown | 98 083 (17.3) | 44 721 (13.6) | 53 362 (22.2) | |
| Socioeconomic status index (quintile), No. (%) | <.001 | |||
| 5 - Highest | 96 074 (18.5) | 53 319 (17.7) | 42 755 (19.6) | |
| 4 | 113 603 (21.9) | 70 259 (23.4) | 43 344 (19.9) | |
| 3 | 108 502 (20.9) | 66 339 (22.1) | 42 163 (19.4) | |
| 2 | 103 510 (19.9) | 61 277 (20.4) | 42 233 (19.4) | |
| 1 - Lowest | 97 276 (18.7) | 49 541 (16.5) | 47 735 (21.9) | |
| Missing or unknown | 49 575 | 27 959 | 21 616 | |
| Area, No. (%) | <.001 | |||
| Urban | 374 456 (72.2) | 214 968 (71.5) | 159 488 (73.1) | |
| Suburban | 69 188 (13.3) | 41 272 (13.7) | 27 916 (12.8) | |
| Rural | 75 322 (14.5) | 44 495 (14.8) | 30 827 (14.1) | |
| Missing or unknown | 49 574 | 27 959 | 21 615 |
a
Other includes American Indian or Alaska Native, Hawaiian or Pacific Islander, and/or multiracial. IQR = interquartile range.