Table 2.
MGUS prevalence in Eswatini and Olmsted County, Minnesota, stratified by age, sex, and light-chain vs conventional isotypea
| Panel A. Eswatini, 2016-2017 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Light-chain MGUS |
Conventional MGUS |
Any MGUS |
|||||||
| Male, n/N (%) | Female, n/N (%) | Total, n/N (%) | Male, n/N (%) | Female, n/N (%) | Total, n/N (%) | Male, n/N (%) | Female, n/N (%) | Total, n/N (%) | |
| 50-59 y | 4/42 (9.52) | 12/81 (14.81) | 16/123 (13) | 0/42 (0) | 1/81 (1.23) | 1/123 (0.813) | 4/42 (9.52) | 13/81 (16.05) | 17/123 (13.82) |
| 60-69 y | 5/29 (17.24) | 5/51 (9.80) | 10/80 (12.5) | 1/29 (3.45) | 2/51 (3.92) | 3/80 (3.75) | 6/29 (20.69) | 7/51 (13.73) | 13/80 (16.25) |
| 70-79 y | 0/21 (0) | 6/29 (20.69) | 6/50 (12) | 2/21 (9.52) | 1/29 (3.45) | 3/50 (6) | 2/21 (9.52) | 7/29 (24.14) | 9/50 (18) |
| 80-89 y | 0/4 (0) | 1/12 (8.33) | 1/16 (6.25) | 0/4 (0) | 2/12 (16.67) | 2/16 (12.5) | 0/4 (0) | 3/12 (25) | 3/16 (18.75) |
| Total | 9/96 (9.38) | 24/173 (13.87) | 33/269 (12.27) | 3/96 (3.13) | 6/173 (3.47) | 9/269 (3.35) | 12/96 (12.5) | 30/173 (17.34) | 42/269 (15.61) |
| Age-standardized prevalence | 22/206 (10.68) | 35/309 (11.33) | — | 5/206 (2.43) | 6/309 (1.94) | — | 27/206 (13.11) | 41/309 (13.27) | — |
| Prevalence standardized for age and sex | — | — | 57/515 (11.1) | — | — | 11/515 (2.14) | — | — | 68/515 (13.20) |
|
Panel B. Olmsted County, MN, 1995-2001 (7) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Light-chain MGUS |
Conventional MGUS |
Any MGUS |
|||||||
| Male, % | Female, % | Total, % | Male, % | Female, % | Total, % | Male, % | Female, % | Total, % | |
| 50-59 y | 0.60 | 0.40 | 0.50 | 2.20 | 1.30 | 1.70 | 2.80 | 1.70 | 2.20 |
| 60-69 y | 1.00 | 0.50 | 0.80 | 3.80 | 2.60 | 3.10 | 4.80 | 3.10 | 3.90 |
| 70-79 y | 1.70 | 0.70 | 1.10 | 5.50 | 4.30 | 4.80 | 7.20 | 5.00 | 5.90 |
| 80-89 y | 1.00 | 1.50 | 1.30 | 8.90 | 6.70 | 7.40 | 9.90 | 8.20 | 8.70 |
| Total | 1.00 | 0.60 | 0.80 | 3.80 | 3.10 | 3.40 | 4.80 | 3.70 | 4.20 |
| Age-standardized prevalence | 1.00 | 0.60 | — | 4.10 | 2.90 | — | 5.10 | 3.50 | — |
| Prevalence standardized for age and sex | — | — | 0.8 | — | — | 3.4 | — | — | 4.2 |
a
MGUS = monoclonal gammopathy of undetermined significance.