Table 1.
Summary of various clinical experimental studies regarding the presence of oral bacteria in Inflammatory bowel disease (IBD).
| Oral Associated Bacteria | Sampling/Size | Methods | Main Findings | References |
|---|---|---|---|---|
|
Fusobacterium nucleatum
Streptococcus |
—Saliva and stool samples/ UC patients (n=42), CD patients (n=185), Controls (n =45) |
16S rRNA gene sequencing | —Increased abundance of presented bacteria in IBD | Jin Imai et al. (14) |
| Candida albicans | —Feces, Oral swabs, colonic mucosa/UC patients (n=72), CD patients (n=18), Controls (n=36) |
PCR-RAPD reaction | —Increased abundance of presented bacteria in IBD | Danuta Trojanowska et al. (55) |
| Fusobacterium nucleatum | —Colonic mucosa/ UC patients (n=4), CD patients (n=17), Controls (n=34) |
qPCR | —Increased abundance of presented bacteria in IBD —high invasive Potential |
Jaclyn Strauss (56) |
| Campylobacter concisus | —Saliva samples/UC patients (n=6),CD patients (n=13),Controls (n=23) | qPCR | —Increased abundance of presented bacteria in IBD | Fang Liu (57) |
| Fusobacterium nucleatum | —Feces samples/UC patients (n=20), CD patients (n=71), Controls (n=43) |
qPCR | —Increased abundance of presented bacteria in IBD. —Correlated with patients’ disease activity |
Hua Liu (58) |
| Klebsiella pneumoniae | —Feces samples/UC patients (n=51), CD patients (n=7), Controls (n=150) |
16S rRNA gene sequences | —Increased abundance of presented bacteria in IBD and exacerbate intestinal diseases | Koji Atarashi (59) |
|
Fusobacterium,Haemophilus, Porphyromonas, Campylobacter |
—Feces samples/CD patients (n=43), Controls (n=18) |
16S rRNA gene sequencing | —Increased abundance of presented bacteria in IBD | Kai Xia (60) |
| Porphyromonas gingivalis | —Feces samples/CD patients (n=11), Controls (n=8) |
16S rRNA gene sequencing | —Increased abundance of presented bacteria in CD | Yu-Chen Lee (61) |
| Streptococcus gallolyticus | —Feces samples/IBD patients (n=44), Controls (n=40) |
qPCR | —Increased abundance of presented bacteria in IBD | Ahmad Farajzadeh Sheikh (62) |
| Campylobacter concisus | —Feces samples/CD patients (n=54), Controls (n=33) |
16S rRNA gene sequences, | —Increased abundance of presented bacteria in CD | Si Ming Man (63) |
| Candida | —Feces samples/ IBD patients (n=235), Controls (n=38) |
16S rRNA gene sequences | —Increased abundance of presented bacteria in IBD | Harry Sokol (64) |
Inflammatory bowel disease (IBD), Ulcerative colitis (UC), Crohn’s disease (CD), Polymerase Chain Reaction Random Amplified Polymorphic DNA reaction (PCR-RAPD reaction).