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(A) Best-fit curves for the lifetime of Vt bound to actin as assessed in Ref. 13 give rise to a parameterized model (see table) with two bound states and one unbound state. (B) Vinculin four-or five helical bundles corresponding to the putative strong and weak bound states of catenin from Refs. 70 and 71. (C) Some of our models of five actin subunits bound to either four and five-helical bundle states of Vt, for probing the force sensitivity of Vt unbinding.
