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. 2024 Aug 9;8:176. doi: 10.1038/s41698-024-00660-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 5 — a Heatmap of pro-inflam and pro-tumor TAMs co-expressed genes for three different TAMs subtypes classification in the IMvigor210 dataset. b Rate of clinical response to immunotherapy in three different TAM subtypes in the IMvigor210 cohort. c Heatmap of pro-inflam and pro-tumor TAMs co-expressed genes for three different TAMs subtypes classification in the PRJEB25780 dataset. d Rate of clinical response to immunotherapy in three different TAM subtypes in the PRJEB25780 cohort. e Heatmap of pro-inflam and protumor TAMs co-expressed genes for three different TAMs subtypes classification in the GSE100797 dataset. f Rate of clinical response to immunotherapy in three different TAM subtypes in the GSE100797 cohort. g Rate of clinical response to immunotherapy in three different TAM subtypes in the ERP105482 cohort. h Rate of clinical response to immunotherapy in three different TAM subtypes in the GSE135222 cohort.