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. Author manuscript; available in PMC: 2024 Aug 9.
Published in final edited form as: J Clin Immunol. 2023 Nov 7;43(8):2208–2220. doi: 10.1007/s10875-023-01593-6

Table 4.

Chronic respiratory conditions in patients with CVID with and without bronchiectasis

Organ/compartment Condition CVID with bronchiectasis (n = 197) CVID w/o bronchiectasis (n = 1273) p value

Nasal Allergic rhinitis (AR) 16 (8.12) 78 (6.13) .28
Chronic rhinosinusitis (CRS) 27 (13.71) 98 (7.70) .01
Nasal polyps 3 (1.52) 7 (0.55) .14
Ear Hearing loss 4 (2.03) 15 (1.18) 0.31
Chronic otitis 1 (0.51) 13 (1.02) 0.71
Eustachian tube dysfunction 2 (1.02) 6 (0.47) .29
Other upper airway Vocal cord dysfunction 1 (0.51) 7 (0.55) 1.00
Lower airway Chronic bronchitis 3 (1.52) 17 (1.34) .74
COPD 25 (12.69) 49 (3.85) .00
Asthma 98 (49.75) 512 (40.22) .01
Lung alveoli PAP 1 (0.51) 4 (0.31) .51
ARDS 3 (1.52) 1 (0.08) .01
Lung Interstitium ILD (ALL) 32 (16.24) 71 (5.58) .00
ILD ns 24 (12.18) 48 (3.77) .00
OP 4 (2.03) 7 (0.55) .048
FIB 4 (2.03) 6 (0.47) .03
IP 2 (1.02) 8 (0.63) .63
LIP 6 (3.05) 11 (0.86) .02
NLH 2 (1.02) 3 (0.24) .14
BO 4 (2.03) 2 (0.16) .00
FB 5 (2.54) 8 (0.63) .02
Nodular lesions (ALL) 8 (4.06) 34 (2.67) .26
Single nodule 1 (0.51) 10 (0.79) 1.00
Multiple nodules 7 (3.55) 24 (1.89) .18
Lung granulomas 10 (5.08) 14 (1.10) .00
Lung vasculature Pulmonary embolism (PE) 2 (1.02) 9 (0.71) .65
Pulmonary arterial hypertension (PAH) 2 (1.02) 6 (0.47) .29
Pleura Pleural compromise (ALL) 11 (5.58) 26 (2.04) .01
Empyema 1 (0.51) 10 (0.79) 1.00
Pleural ns 10 (5.08) 17 (1.34) .00
Other Chest Anatomy 5 (2.54) 18 (1.41) .22
OSA 10 (5.08) 56 (4.40) .71

This table summarizes the details of non-infectious respiratory conditions by compartment. Data are presented as frequency and percentage of patients in each group. Comparisons were made using the chi-square test. Bolding indicates statistical significance (p ≤ .05)