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. 2024 Jun 25;111(2):391–395. doi: 10.4269/ajtmh.23-0306

Table 4.

Performance of SARS-CoV-2 IgG ELISA using dried blood spots compared with serum samples

Serum Samples, n (%) Total
Seropositive Seronegative
Dried blood spots Seropositive 100 (100) 1 (0.5) 101 (34.4)
Seronegative 0 (0) 193 (99.5) 193 (65.6)
Total 100 (100) 194 (100) 294 (100)
Sensitivity (95% CI): 100.0% (96.4–100.0%)
Specificity (95% CI): 99.5% (97.2–100.0%)
Positive Predicted Value (95% CI): 99.0% (93.4–99.9%)
Negative Predicted Value (95% CI): 100.0% (97.6–100.0%)
False-Negative (95% CI): 0% (0–3.6%)
False-Positive (95% CI): 0.5% (0–2.8%)
Cohen’s κ Value (95% CI): 99.2% (97.8–100%)
Lin’s Concordance Correlation Coefficient (95% CI): 97.3% (96.7–97.8%)