Table 3. Set Process Parameters of the Experiments According to the 24-1 Fractional Factorial Design and Experimental Results.
| experiment name | randomized order | pPVP-K12 [w/wFMT%] | f [RPM] | BE [yes or no] | RT [min] (FR [mL/min]) | Form A polymorph content [%] | y [%] |
|---|---|---|---|---|---|---|---|
| FMT_1 | 12 | 2.5 | 400 | yes | 41.25 (20) | 100 | 69.0 |
| FMT_2 | 1 | 2.5 | 400 | no | 82.5 (10) | 100 | 84.0 |
| FMT_3 | 7 | 2.5 | 200 | yes | 82.5 (10) | 100 | 76.4 |
| FMT_4 | 5 | 2.5 | 200 | no | 41.25 (20) | 100 | 69.1 |
| FMT_5 | 8 | 0 | 400 | yes | 82.5 (10) | 11 | 82.3 |
| FMT_6 | 6 | 0 | 400 | no | 41.25 (20) | 78 | 68.0 |
| FMT_7 | 11 | 0 | 200 | yes | 41.25 (20) | 2 | 66.8 |
| FMT_8 | 4 | 0 | 200 | no | 82.5 (10) | 4 | 82.2 |
| FMT_9 | 9 | 1.25 | 300 | yes | 55 (15) | 100 | 69.6 |
| FMT_10 | 10 | 1.25 | 300 | yes | 55 (15) | 100 | 69.2 |
| FMT_11 | 2 | 1.25 | 300 | no | 55 (15) | 100 | 76.6 |
| FMT_12 | 3 | 1.25 | 300 | no | 55 (15) | 100 | 77.1 |