| GZMB+ B cells: | Granzyme B positive B cells with regulatory properties. |
| Induced GZMB+ B cells: | GZMB+ B cells generated according to the in vitro protocol described in Chesneau et al. [19]. |
| Natural GZMB+ B cells: | B cells from donor’s blood or biopsies expressing GZMB without any restimulation in vitro. |
| GZMB− B cells: | B cells used to determine the characteristics of GZMB+ B cells. For the dataset generated after in vitro induction, GZMB− B cells correspond to the conditions that did not receive any stimulation (i.e., total resting B cells after 3 days), as GZMB expression is transient. |
| TOL: | Patients with no immunosuppression for at least one year and with stable creatinine < 150 mmol/L and proteinuria < 1 g/24. |
| STA: | Patients with stable graft function (creatinine < 150 mmol/L and proteinuria < 0.2 g/g creatinine) for at least 3 years under standard immunosuppression (calcineurin inhibitors [CNIs], antimetabolite ± corticosteroids). |
| ABMR: | Patients with histology-proven antibody-mediated rejection. |
| DEG: | Differentially expressed gene. |