Table 1.

Patients’ clinical profiles and anti-AQP4 titers.

Patient	NMO1	NMO2	NMO3	NMO4	NMO5	NMO6
Age	64	62	52	28	49	59
Sex	F	F	F	F	F	M
Clinical phenotype	C	ON	ON	ON + C	APS + My	ON + APS + My
Relapse or first attack	Relapse	Relapse	Relapse	First attack	First attack	First attack
EDSS on nadir	7.5	6	5	4	5	5
EDSS after treatment	6	5	5	1.5	2.5	3
Anti-AQP4 titer of serum at attack	1:524,288	1:32,768	1:131,072	1:4096	1:1024	1:1024
Anti-AQP4 titer of purified-IgG	1:131,072	1:262,144	1:32,768	1:4096	1:1024	1:256

Abbreviations: APS, area postrema syndrome; C, cerebral lesion; EDSS, expanded disability status scale; My, myelitis; ON, optic neuritis.