Table 3.
Previous evidence regarding functional recovery after PN.
| Author(s) | Type of Study | Sample Size | Ischemia Technique | Renal Function Outcomes |
|---|---|---|---|---|
| Thompson 2010 [18] | Retrospective | 362 | Warm ischemia | -AKI: 19% -New CKD IV: 17% -Longer WIT: OR 1.05 × min |
| Mir 2013 [16] |
Retrospective | 35 57 |
Hypothermia Limited warm |
-GP/VS: 101% vs. 92% -%PVS: Effect 36.9 (29.5,43.3) |
| Greco 2019 [9] |
Systematic review | 22,626 | Cold Warm Zero |
Log2 GFR mean changes: −1.37 (−3.42 to 0.68) −1.00 (−2.04 to 0.03) −0.71 (−1.15 to−0.27) |
| Anderson 2019 [7] |
RCT | 40 40 |
Zero Warm |
%GFR change: −10.7% vs. −9.4% %SRF change: −11.2% vs. −11.8% |
| Antonelli 2021 [19] |
RCT | 164 160 |
Zero Warm |
%GFR change: −5.1% vs. −6.2% %SRF change: −2% vs. −2.5% |
| Present study | Retrospective | 21 | Zero | -%GFR change: −12% -New CDK IV: 0% |
Abbreviations: RCT—randomized control trial; AKI—acute kidney injury; CKD—chronic kidney disease; WIT—warm ischemia time; GP/VS—recovery of nephron function (%GFR preservation/%volume saved); PVS—parenchyma volume saved; GFR—glomerular filtration rate; SRF—split renal function.