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. 2024 Jul 26;16(15):2653. doi: 10.3390/cancers16152653

Table 2.

Full descriptions of non-breast cancer studies identified during the literature search.

Author and Year Cancer Type LAN Exposure Study Design Sampling Frame Participant Source LAN Assessment Reference Group Exposure Adjusted OR/RR Adjusted/Matched Factors
Walasa, 2018 [49] Colorectal Indoor Case-Control Population-based Western Australia Bowel Health Study Self-reported No shifts with Light at night 7.5+ years of shiftwork with light at night 0.91 (0.55–1.53) age, education, SES, smoking, and alcohol use
Garcia-Saenz, 2018 [45] Prostate Indoor Case-Control Population-based MCC-Spain Self-reported Total Darkness Very Illuminated 2.79 (1.55–5.04) age, center, educational level, socioeconomic status, UVI, BMI, tobacco, family history of breast/prostate cancer, chronotype, menopausal status (breast cancer), and mutual adjustment for other light exposures
Garcia-Saenz, 2018 [45] Prostate Outdoor Case-Control Population-based MCC-Spain Measured Outdoor LAN Q1 Outdoor LAN Q3 0.56 (0.38–0.84) age, center, educational level, socioeconomic status, UVI, BMI, tobacco, family history of breast/prostate cancer, chronotype, menopausal status (breast cancer), and mutual adjustment for other light exposures
Measured Outdoor Blue LAN Q1 Outdoor Blue LAN Q3 2.05 (1.38–3.03)
Garcia-Saenz, 2020 [46] Colorectal Outdoor Case-Control Population-based MCC-Spain Measured Outdoor LAN Q1 Outdoor LAN Q3 0.9 (0.7–1.1) Area, age, sex, educational level, WCRF score, Urban Vulnerability Index, family history, smoking habits, sleeping problems, and sleep duration
Measured Outdoor Blue LAN Q1 Outdoor Blue LAN Q3 1.7 (1.3–2.3)
Zhong, 2020 [40] NHL Outdoor Prospective Cohort Population-based California Teachers Study Measured Outdoor LAN Q1 Outdoor LAN Q5 1.32 (1.05–1.66) age, race, SES, BMI, smoking, alcohol, and FH of NHL
Xiao, 2021 [39] Pancreatic Outdoor Prospective Cohort Population-based NIH-AARP Measured Outdoor LAN Q1 Outdoor LAN Q5 1.24 (1.03–1.49) Age, sex, race, education, marital status, state of residence, median home value, poverty rate, and population density at the census tract level
Zhang, 2021 [38] Thyroid Outdoor Prospective Cohort Population-based NIH-AARP Measured Outdoor LAN Q1 Outdoor LAN Q5 1.55 (1.18–2.02) Age, sex, race, education, marital status, state of residence, median home value, poverty rate, and population density at the census tract level
Park, 2022 [37] Liver Outdoor Prospective Cohort Population-based NIH-AARP Measured Outdoor LAN Q1 Outdoor LAN Q5 0.96 (0.77–1.20) age, sex, race/ethnicity, education, BMI, diabetes, aspirin use, coffee consumption, night-time sleep duration, state, income, and urban–rural code
Medgyesi, 2023 [36] Endometrial Outdoor Prospective Cohort Population-based NIH-AARP Measured Outdoor LAN Q1 Outdoor LAN Q5 0.93 (0.77–1.1) Age, race/ethnicity, poverty, state, BMI, years of OC use, age at menopause, HRT use, parity, PM2.5, and metro-rural area