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. 2024 Jul 24;16(15):2636. doi: 10.3390/cancers16152636

Table 2.

Average fold change in MMP2 and N-cadherin levels in exosomes and recipient cells.

ABC Transporter Cell Lines Exosomes
Control GH Doxo Doxo + GH Doxo + GH + Peg
MMP2 Malme-3M 1.0 1.6 1.6 2.0 1.0
SK-MEL-28 1.0 2.0 2.1 2.3 1.4
SK-MEL-30 1.0 1.9 1.4 2.0 0.7
N-cadherin Malme-3M 1.0 1.0 2.0 3.5 1.6
SK-MEL-28 1.0 0.8 0.8 0.8 1.9
SK-MEL-30 1.0 4.5 1.7 4.0 2.9
Recipient Cells
ExoControl ExoGH ExoDoxo ExoDoxo+GH ExoDoxo+GH+Peg
MMP2 Malme-3M 1.0 1.2 1.1 1.0 0.8
SK-MEL-28 1.0 0.8 1.9 0.8 0.8
SK-MEL-30 1.0 1.6 1.8 2.0 1.4
N-cadherin Malme-3M 1.0 2.5 1.9 3.1 1.5
SK-MEL-28 1.0 2.0 1.4 1.9 1.2
SK-MEL-30 1.0 1.0 1.2 1.0 0.7

Average fold change is calculated based on corresponding controls.