Table 2.
ABC Transporter | Cell Lines | Exosomes | ||||
---|---|---|---|---|---|---|
Control | GH | Doxo | Doxo + GH | Doxo + GH + Peg | ||
MMP2 | Malme-3M | 1.0 | 1.6 | 1.6 | 2.0 | 1.0 |
SK-MEL-28 | 1.0 | 2.0 | 2.1 | 2.3 | 1.4 | |
SK-MEL-30 | 1.0 | 1.9 | 1.4 | 2.0 | 0.7 | |
N-cadherin | Malme-3M | 1.0 | 1.0 | 2.0 | 3.5 | 1.6 |
SK-MEL-28 | 1.0 | 0.8 | 0.8 | 0.8 | 1.9 | |
SK-MEL-30 | 1.0 | 4.5 | 1.7 | 4.0 | 2.9 | |
Recipient Cells | ||||||
ExoControl | ExoGH | ExoDoxo | ExoDoxo+GH | ExoDoxo+GH+Peg | ||
MMP2 | Malme-3M | 1.0 | 1.2 | 1.1 | 1.0 | 0.8 |
SK-MEL-28 | 1.0 | 0.8 | 1.9 | 0.8 | 0.8 | |
SK-MEL-30 | 1.0 | 1.6 | 1.8 | 2.0 | 1.4 | |
N-cadherin | Malme-3M | 1.0 | 2.5 | 1.9 | 3.1 | 1.5 |
SK-MEL-28 | 1.0 | 2.0 | 1.4 | 1.9 | 1.2 | |
SK-MEL-30 | 1.0 | 1.0 | 1.2 | 1.0 | 0.7 |
Average fold change is calculated based on corresponding controls.