Table 4.
Median and interquartile range values of changes in CT lung lesion volume normalized for the predicted total lung capacity and 3D-AD.
| Whole Lung | Subpleural Region c | Inner Region | p-Value a | |
|---|---|---|---|---|
| Categorical change in CT lesion variables b | ||||
| ΔEmphysema (%) | 0.22 (0.03–0.90) | 0.10 (0.01–0.34) | 0.05 (−0.00–0.47) | 0.40 |
| ΔConsolidation + Fibrosis (%) | 0.25 (0.56–0.71) | 0.15 (0.02–0.38) | 0.06 (0.00–0.31) | 0.01 |
| ΔGround-glass opacity (%) | 0.12 (−1.37–1.43) | −0.06 (−0.75–0.58) | 0.10 (−0.54–0.87) | 0.001 |
| ΔReticulation (%) | 0.52 (−0.07–1.35) | 0.36 (−0.05–0.87) | 0.04 (−0.04–0.45) | 0.003 |
| ΔHoneycombing + Traction bronchiectasis (%) | 0.16 (0.01–0.81) | 0.08 (0.01–0.34) | 0.047 (−0.01–0.26) | <0.001 |
| ΔNormal (%) | 0.00 (−0.01–0.03) | −1.82 (−4.01–−0.06) | −2.54 (−8.47–0.97) | 0.02 |
| ΔFibrotic lesion (%) | 1.08 (0.15–2.69) | 0.70 (0.22–1.60) | 0.21 (0.00–1.12) | <0.001 |
| ΔTotal CT lung volume (cc) | −183 (−469–131) | |||
| 3D-AD (mm) | 5.0 (3.3–6.7) | 5.2 (3.6–7.1) | 4.7 (3.0–6.4) | <0.001 |
Numbers in parentheses are the interquartile range. a Wilcoxon’s signed-rank test to compare CT parameters between subpleural and inner lung regions. b Result of subtraction initial CT lung lesion from follow up CT lung lesion. c The 10 mm-width area of the lung surface. 3D-AD, three-dimensional average displacement.