Table 1.
Demographic, comorbidities, and perioperative data according to the CONUT score groups.
| Total | Low CONUT (n = 385) |
High CONUT (n = 51) |
p-Value | |
|---|---|---|---|---|
| Age (years) | 55 (46, 62) | 54 (46, 62) | 59 (50, 66) | 0.022 |
| Sex (Female) | 231 (53.0%) | 205 (53.2%) | 26 (51.0%) | 0.761 |
| BMI (kg/m2) | 22.9 (20.8, 25.5) | 23.1 (20.9, 25.6) | 21.7 (20.2, 23.9) | 0.020 |
| ASA PS class | 2 (2, 3) | 2 (2, 3) | 3 (2, 3) | <0.001 |
| Comorbidities | ||||
| Hypertension | 115 (26.4%) | 100 (26.0%) | 15 (29.4%) | 0.601 |
| DM | 57 (13.1%) | 52 (13.5%) | 5 (9.8%) | 0.461 |
| CAOD | 9 (2.1%) | 5 (1.3%) | 4 (7.8%) | 0.013 |
| COPD | 14 (3.2%) | 12 (3.1%) | 2 (3.9%) | 0.673 |
| Old tuberculosis | 14 (3.2%) | 13 (3.4%) | 1 (2.0%) | >0.999 |
| Hepatitis | 12 (2.8%) | 10 (2.6%) | 2 (3.9%) | 0.640 |
| CKD | 8 (1.8%) | 6 (1.6%) | 2 (3.9%) | 0.238 |
| Anemia | 197 (45.2%) | 153 (39.7%) | 44 (86.3%) | <0.001 |
| Primary origin | ||||
| Colorectal | 255 (58.5%) | 234 (60.8%) | 21 (41.2%) | 0.008 |
| Gastric | 34 (7.8%) | 28 (7.3%) | 6 (11.8%) | 0.265 |
| Appendiceal/PMP | 121 (27.8%) | 101 (26.2%) | 20 (39.2%) | 0.052 |
| Mesothelioma | 5 (1.1%) | 4 (1.0%) | 1 (2.0%) | 0.465 |
| Pancreatic | 2 (0.5%) | 2 (0.5%) | 0 (0%) | >0.999 |
| Small bowel | 4 (0.9%) | 3 (0.8%) | 1 (2.0%) | 0.393 |
| Others | 15 (3.4%) | 13 (3.4%) | 2 (3.9%) | 0.691 |
| Preoperative lab data | ||||
| CONUT score | 1 (0, 2) | 1 (0, 2) | 5 (4, 7) | <0.001 |
| Albumin (g/dL) | 4.1 (3.8, 4.4) | 4.2 (3.9, 4.4) | 3.2 (2.9, 3.5) | <0.001 |
| Lymphocyte (/μL) | 1655 (1303, 2150) | 1740 (1425, 2225) | 1020 (760, 1400) | <0.001 |
| Cholesterol (mg/dL) | 177 (150, 205) | 181 (158, 208) | 131 (111, 148) | <0.001 |
| Glucose (mg/dL) | 101 (93, 111) | 101 (93, 111) | 102 (94, 119) | 0.394 |
| Creatinine (mg/dL) | 0.68 (0.57, 0.85) | 0.68 (0.58, 0.85) | 0.66 (0.50, 0.83) | 0.112 |
| Hemoglobin (g/dL) | 12.6 (11.2, 13.8) | 12.8 (11.4, 13.9) | 10.4 (9.3, 11.4) | <0.001 |
| Intraoperative data | ||||
| Operation Time (min) | 505 (378, 676) | 505 (380, 675) | 493 (354, 713) | 0.859 |
| Fluid input (mL/h) | 739 (633, 859) | 743 (640, 856) | 697 (625, 888) | 0.537 |
| Urine output (mL/h) | 115 (77, 162) | 115 (79, 162) | 100 (63, 162) | 0.365 |
| Bleeding (mL) | 900 (400, 1600) | 900 (400, 1600) | 700 (300, 1600) | 0.574 |
| Transfused packed RBC (mL) | 0 (0, 365) | 0 (0, 262) | 0 (0, 716) | 0.008 |
| PCI score | 14 (5, 26) | 14 (5, 26) | 18 (8, 39) | 0.022 |
| CC score | 0 (0, 1) | 0 (0, 1) | 1 (0, 2) | 0.003 |
Values are median (interquartile range) or number (%). A low CONUT score was defined as a CONUT score of 0–3, whereas a high CONUT score was defined as a CONUT score of 4–12. Abbreviations: CONUT, Controlling Nutritional Status; BMI, body mass index; ASA PS class, American Society of Anesthesiologists physical status class; DM, diabetes mellitus; CAOD, coronary artery occlusive disease; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; PMP, Pseudomyxoma peritonei; RBC, red blood cell; PCI, peritoneal cancer index; CC, completeness of cytoreduction.