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. 2024 Jul 31;16(15):2727. doi: 10.3390/cancers16152727

Table 4.

Cox regression analysis of chosen variables for predicting overall mortality.

Variable Univariable Multivariable
Crude HR (95% CI) p-Value Adjusted HR (95% CI) p-Value
High CONUT 1.645 (1.157, 2.340) 0.006 1.777 (1.182, 2.669) 0.006
Age (years) 1.000 (0.991, 1.010) 0.998
Sex (Female) 0.906 (0.713, 1.151) 0.418
BMI (kg/m2) 0.951 (0.919, 0.984) 0.004 0.985 (0.949, 1.022) 0.416
ASA PS class ≥ 3 1.314 (1.031, 1.675) 0.027 1.120 (0.857, 1.463) 0.408
Hypertension 1.073 (0.819, 1.405) 0.611
DM 0.883 (0.610, 1.277) 0.507
CAOD 0.839 (0.346, 2.033) 0.697
COPD 0.446 (0.184, 1.081) 0.074
Old tuberculosis 0.920 (0.455, 1.860) 0.817
Hepatitis 0.884 (0.417, 1.872) 0.747
CKD 1.302 (0.537, 3.160) 0.559
Anemia 1.340 (1.055, 1.703) 0.017 1.046 (0.801, 1.366) 0.742
Glucose (mg/dL) 1.001 (0.996, 1.006) 0.624
Creatinine (mg/dL) 1.155 (0.820, 1.629) 0.410
Operation Time (h) 1.043 (1.006, 1.082) 0.023 1.054 (1.004, 1.106) 0.033
Fluid input (mL/h) 1.000 (0.999, 1.000) 0.297
Urine output (mL/h) 0.999 (0.997, 1.000) 0.088
Transfused packed RBC (mL) 1.000 (1.000, 1.001) 0.011 1.000 (1.000, 1.000) 0.790
PCI score ≥ 20 2.200 (1.719, 2.815) <0.001 1.829 (1.315, 2.543) <0.001
CC score ≥ 2 2.724 (2.069, 3.586) <0.001 2.931 (2.039, 4.212) <0.001
Pathology
 Colorectal Reference Reference
 Gastric 2.022 (1.385, 2.951) <0.001 1.571 (1.038, 2.379) 0.033
 Appendiceal/PMP 0.418 (0.298, 0.588) <0.001 0.227 (0.156, 0.331) <0.001
 Others 1.012 (0.629, 1.629) 0.959 0.477 (0.275, 0.827) 0.008

A high CONUT score was defined as a CONUT score of 4–12. Abbreviations: HR, hazard ratio; CONUT, Controlling Nutritional Status; BMI, body mass index; ASA PS class, American Society of Anesthesiologists physical status class; DM, diabetes mellitus; CAOD, coronary artery occlusive disease; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; RBC, red blood cell; PCI, peritoneal cancer index; CC, completeness of cytoreduction; PMP, Pseudomyxoma peritonei.