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. 2000 Nov 1;28(21):4219–4224. doi: 10.1093/nar/28.21.4219

Figure 6.

Figure 6

Activation ability of IRF-2/IRF-2s in reporter gene assays. IRF-2 or IRF-2s expression plasmid or no IRF was transfected into TM3 cells with the CIITA type IV promoter/luciferase vector and the TK promoter/renilla luciferase vector (as an internal control). Effect of IFN-γ (A) and IFN-α (B) on IRF-2/IRF-2s-induced reporter gene expression. Open boxes denote no stimulation and dark grey boxes IFN stimulation (24 h). The relative promoter activity is calculated as the ratio of firefly luciferase to renilla luciferase activity. The mean of three experiments is shown (± SE).