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ROS/P38-MAPK/NF-κB signaling pathway was implicated in the regulation of cartilage endplate cells senescence induced by ox-LDL/LOX-1. A-D Western blot and quantitative analysis were performed to evaluate the expression of cell senescence/calcification-related proteins as well as P38-MAPK/NF-κB pathway-related proteins. E, F P16 and NF-κB representative immunofluorescence staining results. Compared to ox-LDL group, *p < 0.05, **p < 0.01, ns indicated non-significance difference
