Table 2.
Univariate and multivariate analysis of the factors related to postoperative short-term (6-week) mortality
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Baseline Hb | 0.89 (0.67–1.16) | 0.384 | ||
| Postoperative nadir Hb | 0.75 (0.57-1.00) | 0.048 | ||
| Predischarge Hb | 0.62 (0.44–0.88) | 0.007 | 0.61 (0.42–0.87) | 0.006 |
| Nadir Hb drift | ||||
| Absolute | 0.85 (0.64–1.12) | 0.239 | ||
| Percentage | 0.05 (0.00-2.38) | 0.127 | ||
| Predischarge Hb drift | ||||
| Absolute | 0.80 (0.61–1.06) | 0.116 | ||
| Percentage | 0.03 (0.00-1.66) | 0.087 | ||
| Age | 0.98 (0.94–1.03) | 0.522 | ||
| Primary tumor site | ||||
| Slow growth | Ref | Ref | ||
| Moderate growth | 7.46 (0.85–65.34) | 0.070 | 6.03 (0.65–55.86) | 0.114 |
| Rapid growth | 9.49 (1.18–76.38) | 0.034 | 8.57 (1.02–72.25) | 0.048 |
| Visceral metastases | 2.70 (0.90–8.14) | 0.077 | ||
| No. of spine metastases | ||||
| 1 level | Ref | |||
| 2 levels | 2.25 (0.57–8.90) | 0.250 | ||
| ≥ 3 levels | 0.79 (0.24–2.55) | 0.688 | ||
| Other bone metastases | 2.47 (0.69–8.86) | 0.167 | ||
| ECOG | ||||
| Score 0–2 | Ref | |||
| Score 3–4 | 2.08 (0.57–7.58) | 0.265 | ||
| ASIA | ||||
| A to C | Ref | Ref | ||
| D or E | 0.26 (0.09–0.75) | 0.013 | 0.16 (0.05–0.49) | 0.002 |
| Transfusion | 1.17 (0.40–3.48) | 0.772 | ||
| Blood loss > 1000 ml | 0.76 (0.26–2.26) | 0.624 | ||
| Surgery type | ||||
| Corpectomy with stabilization | Ref | |||
| Decompression and stabilization | 0.99 (0.28–3.49) | 0.988 | ||
| Decompression alone | 1.37 (0.42–4.46) | 0.606 | ||
| 30-day morbidity | 2.49 (0.87–7.16) | 0.090 |
ECOG, Eastern Cooperative Oncology Group; ASIA, American Spinal Injury Association